FOUR LOVE POEMS
not been in love
I would have passed
the flowers by
has a sword
and the Lady
Love is only pain and sorrow
yesterday, today, and tomorrow.
One door in and no way out.
Only pain to sing about
met the Candle …
Rochester Unvi. Study shows brain cleaning through sleep through an active glymphatic system
The new findings hinge on the discovery last year by Nedergaard and her colleagues of a previously unknown system of waste removal that is unique to the brain. The system responsible for disposing cellular waste in the rest of the body, the lymphatic system, does not extend to the brain. This is because the brain maintains its own closed “ecosystem” and is protected by a complex system molecular gateways – called the blood-brain barrier – that tightly control what enters and exits the brain.
Sleep was first a chance to end the eating/digestion period, regroup needed water and hormones for next day digestion, and prepare waste out -bowel movement.
This evolved to include a brain resting period to clean out the brain (See study and video above) But more exactly a cleaning out of all BBB blood brain barrier places (brain, testes, eyes, ears, joints, spine)
Now why the NREM and REM?
My first guess is NREM is ‘house maintenance’ that includes getting digestive tract ready, flush all BBB sites, and deliver some hormones.
REM is waste out or a type of flush out of waste after the NREM period.
Still looking at the BBB, blood brain barrier and sleep. Start with the above study about the glymphatic system cleansing the brain at night .
Maybe it’s part of a bigger cleansing – that might include other parts of the blood barrier system (testis, joints, spine, etc). Maybe this is why we sleep.
Found this – see info below: What was interesting to me and perhaps a connection, is that
the Pineal Gland is outside the BBB, AND secretes melatonin.
So what is the connection
Pineal gland is awake during sleep, secretes the sleep melatonin, is outside the BBB, is awake while glymphatic cleansing of brain in sleep.
So does that mean that sleep is for glymphatic cleaning of all blood barriers, or is it all body of which this is part or….
The blood-brain barrier prevents toxic substances, large molecules, and neurotransmitters released in the blood from entering the brain.
Four areas of the brain are not protected by the blood-brain barrier. These areas include the posterior pituitary gland, pineal gland, the median eminence of the hypothalamus and the area postrema.
Posterior Pituitary Gland
The pituitary gland releases the hormones oxytocin, which controls milk release, and vasopressin, which regulates water balance. The pituitary gland is not covered by the blood-brain barrier because the hormones it secretes need to go into circulation and pass through the rest of the body.
The pineal gland secretes the hormone melatonin, which controls circadian and seasonal rhythms, or sleep/wake cycles. The pineal gland is not covered by the blood brain-barrier because it secretes the hormone into the bloodstream.
Median Eminence of the Hypothalamus
The median eminence of the hypothalamus connects the hypothalamus to the pituitary gland. The median eminence is not covered by the blood brain-barrier because hormones secreted by the pituitary gland collect in this region before being secreted into the bloodstream.
The area postrema is not covered by the blood brain-barrier because it senses toxins in the blood that the other parts of the brain are protected from. The area postrema triggers nausea and vomiting to prevent further ingestion of toxins.
BIG THREE CHALLENGE. Most of the music business (80%) is controlled by 3 companies, Universal, Sony, Warners. This is an open challenge for those three.
CHALLENGE: Here is a list of nitmakers from 1955-75. Big 3, see if you can match it from your roster of hit songs from 1995-Now.
When I was growing up we had a consistent stream of hits. We thought they would never end. (Time period about 1955-1975)
There were the major artists: Elvis, Beatles, Rolling Stones, Dylan, Beach Boys, etc.
But even more important there were so many artists that had at least a string of 3,4,5 or 6 major hits. Never in history was there such an out pouring of hit records.
For fun I began to make my list of
THREE TO SIX – STRING OF HITS Club
Help me, won’t you? Add to the list or tell me who doesn’t belong. Here’s a start:
Jerry Lee Lewis
Ike and Tina Turner
Dion and the Belmonts
Little Anthony and the Imperials
Bill Haley and the Comets
The Righteous Brothers
The Everly Brothers
Peter Paul and Mary
The Kingston Trio
Freddie and the Dreamers
Gerry and the Pacemakers
Peter and Gordon
Chad and Jeremy
Dave Clark Five
Simon and Garfunkel
Sonny and Cher
Tommy James and the Shondells
Gary Puckett and the Union Gap
Jan and Dean
Sly and the Family Stone
The Righteous Brothers
Mammas and Pappas
Paul Revere and the Raiders
Martha and the Vandelas
Crosby Stills Nash and Young
The Young Rascals
The Lovin Spoonful
Herb Alpert and theTijuana Brass
The Guess Who
Creedence Clearwater Revival
Blood, Sweat, and Tears
Gary Lewis and the Playboys
Olivia Newton John
PLUS these add ons I missed
Nat King Cole
Gladys Knoight & The Pips
Three Dog Night
The Guess Who,
The Four Lads
The Grass Roots
Billy J. Kramer and The Dakotas
Three Dog Night
Billy Joe Royal
The Grass Roots
Jay and the Americans
Spanky & Our Gang
Dovells /Len Barry
Gary U.S. Bonds
Frankie Lymon and the Teenagers
Ronny and the Daytonas
Tony Orlando and Dawn
The Wrecking Crew (assorted studio musicians)
New Christy Minstrels
Soundtracks that had 3 or more hit songs.
Ben E. King
Shangri – Las
Gladys Knight and the Pips
Sam The Sham and The Pharaohs
Alvin and the Chipmonks
Now corporate music, you do your best music list from 1995- 2015 and let’s compare.
Seems to me that we have a new way to transfer genes that is outside the genome. Support for the idea is growing stronger.
Transfer bacteria from mother to child (transfer her bacterial genes to child’s gut)
Here is another study and a quote from it
Quote: While many questions remain, it’s pretty much taken for granted that the microbial communities of the placenta, vagina, and breast milk are important for fetal and infant development.