Cortisol – Cushing’s Disease, Addison’s Disease + Weight problems

By using two opposite diseases as guide, I can suggest a connection between overweight and underweight, and the type of stress the person faced in infancy. Overweight = outside the body fight and flight stress, and underweight – inside the body infection trauma.

Start with these facts:

What does cortisol do? Cortisol is a stress hormone, that helps the body protect itself when under immediate stress.

Too much cortisol – Cushing’s disease OBESITY, HIGH BLOOD PRESSURE, DIABETES. Compare with


That suggests that there are two stresses:

inside the body stress = infection
outside the body stress = fight or flight response to stress

So, using the two diseases as guide, it would seem that

1. overweight has too much cortisol from either
low infection and/or
high fight or flight response to stress

That means that high cortisol represses the immune system, to marshal it’s stress fighting for outside the body stress.

2. underweight has too little cortisol from either
high infection and/or
low fight or flight response to stress.
That means that low cortisol supports the immune system, to fight infection within.

So where the trauma comes from determines high or low cortisol. I would go further and say this trauma may be an unconscious pattern that is most likely set up in infancy or puberty – the two major biological periods of change in a growing child.

The fix for the trauma is not more or less cortisol; but the resolution of the stress trauma or infection trauma that caused the cortisol level.

Thinking about this the first thing that comes to mind is our obesity epidemic.
It could be too much cortisol that comes from either/or

too little infection ( and this generation is probably less exposed to infection)
too much stress (again this generation may be under more stress than others)

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2 Responses to “Cortisol – Cushing’s Disease, Addison’s Disease + Weight problems”

  1. musea Says:

    Puberty, would trigger these two major traumas, and make that an even more difficult time for the child.

  2. musea Says:

    Cortisol is a 7 day cycle stress hormone.
    Quote: Research has uncovered many conditions about us humans that seem to rise and fall in seven-day cycles. They include: heartbeat, blood pressure, body temperature, hormone levels, acid content in blood, red blood cell count, oral temperature, female breast temperature, urine chemistry and volume, the ratio between two important neurotransmitters: norepinephrine and epinephrine, and the flow of several body chemicals such as the stress-coping hormone cortisol

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